Questions in the Gastroenterology and Liver Diseases Forum have been answered by Dr. Kevin Pho who is board certified in Internal Medicine and by doctors from Henry Ford Health System.

Question Title: Accutane triggers Crohn's and UC in unsuspected many cases

Forum: The Gastroenterology and Liver Diseases Forum
Topic: Crohn's


Alert! I have a growing list of patients in whom Accutane for acne triggered a lifelong serious illness called "inflammatory bowel disease" (Crohn's Disease and Ulcerative Coilitis). It is often first misdiagnosed as "irritable bowel syndrome," and may develop while the patient is on Accutane of months or even years afterward. Its relationship is posted as a "WARNING" in the PDR, although most dermatologists and gastroenterologists are unknowledgeable about the possible connection. Please contact us if you are on or have been on Accutane and have any abnormal GI symptoms--cramping, gaseousness, diarrhea, blood in stool.We will tell you how yo file an adverse drug reaction report with the FDA and add your name to the list for an important epidemiological study we must convince the FDA to conduct.I will share our report with anyone interested, as I just have with the FDA, ACG, AGA, and CCFA. Accutane NOT recommended for IBD patients. Please be in touch.

Dear Laurel,

Thank you for this interesting new information. We will await further studies and research that confirm this finding.


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