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Complementary Medicine Community
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Mighty mice may hold key to Alzheimer's breakthrough
by deepdiver, Nov 28, 2008 02:14PM
Mighty mice may hold key to Alzheimer's breakthrough
You know, mice are really the unsung heroes of medicine. We give these little critters just about every disease under the sun, and then we inject them with test cures that, as often as not, kill them.
It's a rough gig.
But, every now and then, these remarkable rodents help us see our way clear to some breakthrough cures. And it looks like they may have done it again.
Researchers are the University of California at Irvine just wrapped up a study where they gave experimental mice Alzheimer's disease (I told you, these little fellas have it tough). They then gave these mice doses of nicotinamide, a form of vitamin B3 found in many foods, including chicken, fish, pork, peanuts, sunflower seeds and turkey, to see if there was any improvement.
The results were nothing short of amazing. The mice with Alzheimer's saw their memory improve, but get this – even the mice who didn't have Alzheimer's got a cognitive boost.
In Alzheimer's disease, a protein called tau clogs brain cells and tangles connections. Scientists believe vitamin B3 untangles these connections.
As a next step, researchers will sign up human Alzheimer's patients to see if vitamin B3 will work for them.
That's going to put some lab mice out of work. But I'm guessing they won't mind one bit.
DR.I
You know, mice are really the unsung heroes of medicine. We give these little critters just about every disease under the sun, and then we inject them with test cures that, as often as not, kill them.
It's a rough gig.
But, every now and then, these remarkable rodents help us see our way clear to some breakthrough cures. And it looks like they may have done it again.
Researchers are the University of California at Irvine just wrapped up a study where they gave experimental mice Alzheimer's disease (I told you, these little fellas have it tough). They then gave these mice doses of nicotinamide, a form of vitamin B3 found in many foods, including chicken, fish, pork, peanuts, sunflower seeds and turkey, to see if there was any improvement.
The results were nothing short of amazing. The mice with Alzheimer's saw their memory improve, but get this – even the mice who didn't have Alzheimer's got a cognitive boost.
In Alzheimer's disease, a protein called tau clogs brain cells and tangles connections. Scientists believe vitamin B3 untangles these connections.
As a next step, researchers will sign up human Alzheimer's patients to see if vitamin B3 will work for them.
That's going to put some lab mice out of work. But I'm guessing they won't mind one bit.
DR.I
Member Comments (1)
by margypops, Nov 28, 2008 04:43PM
To: deepdiver
Another little gem from you, I have relative who is suffering from something ...he works with Toxins in the wood, boat building industry , I had thought it was Alzheimers , and of course as he wont go for an evaluation, I still dont know if it is Toxins or something like Picks, as those are his symptoms, So perhaps B3 will help him whatever he has.I did research into Neuro Toxins and had a communication with a Dr Skinner who said his symptoms sounded like Neurotoxicity, it is Dr Skinners specialty and he talks about it round the country.So I am thinking that he could take B3 to see if it helps,that and trying to tell him to work with something safer. I guess my health food store will have it,
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