Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.

Hepatitis Social Community

Post a Question Back to Forum
 | 
MedHelp Member's Question

THE VIRUS

by Rockerforlife, Nov 30, 2008 09:37AM
HCV is a small (40 to 60 nanometers in diameter), enveloped, single-stranded RNA virus of the family Flaviviridae and genus hepacivirus. Because the virus mutates rapidly, changes in the envelope proteins may help it evade the immune system. There are at least six major genotypes and more than 50 subtypes of HCV. The different genotypes have different geographic distributions. Genotypes 1a and 1b are the most common in the United States (about 75 percent of cases). Genotypes 2 and 3 are present in only 10 to 20 percent of patients. There is little difference in the severity of disease or outcome of patients infected with different genotypes. However, patients with genotypes 2 and 3 are more likely to respond to interferon treatment

http://digestive.niddk.nih.gov/ddiseases/pubs/chronichepc/
Member Comments (54)

by Rockerforlife, Nov 30, 2008 09:39AM
Viral levels as measured by HCV RNA do not correlate with the severity of the hepatitis or with a poor prognosis (as in HIV infection); but viral load does correlate with the likelihood of a response to antiviral therapy. Rates of response to a course of peginterferon and ribavirin are higher in patients with low levels of HCV RNA. There are several definitions of a “low level” of HCV RNA, but the usual definition is below 800,000 IU (~ 2 million copies) per mL.

by Rockerforlife, Nov 30, 2008 09:42AM
My baseload VL count is 21 million....i just hope the PI`s i am abouit to take this friday will knock that number down to zero

by Rockerforlife, Nov 30, 2008 09:49AM
Ribavirin is excreted largely by the kidneys. Patients with renal disease can develop hemolysis that is severe and even life-threatening. Patients who have elevations in serum creatinine above 2.0 mg per deciliter (dL) should not be treated with ribavirin.

by Marcia2202, Nov 30, 2008 09:54AM
To: Rock
Don't worry bro', you're gonna knock the krap out of them viruses.... After the glimpse I got, I can assure you that! When them viruses get a glimpse of you, they will run away feeling so ug and embarrassed hanging around a handsome guy like that....

by Rockerforlife, Nov 30, 2008 09:55AM
Dosing
Two forms of peginterferon have been developed and studied in large clinical trials: peginterferon alfa-2a (Pegasys: Hoffman La Roche, Nutley, NJ) and peginterferon alfa-2b (Pegintron: Schering-Plough Corporation, Kenilworth, NJ). These two products are roughly equivalent in efficacy and safety, but have different dosing regimens.

Peginterferon alfa-2a is given subcutaneously in a fixed dose of 180 micrograms (mcg) per week.

Peginterferon alfa-2b is given subcutaneously weekly in a weight-based dose of 1.5 mcg per kilogram (kg) per week (thus in the range of 75 to 150 mcg per week).

Ribavirin is an oral medication, given twice a day in 200-mg capsules for a total daily dose based upon body weight. The standard dose of ribavirin is 1,000 mg for patients who weigh less than 75 kg (165 pounds) and 1,200 mg for those who weigh more than 75 kg. In certain situations, an 800-mg dose (400 mg twice daily) is recommended (see Duration).

by Rockerforlife, Nov 30, 2008 10:00AM
I cant believe im about to shot #5 already....and start the Boceprerir this friday....the BOC is a red blood cell killer,just like the riba....im ready for the epo too...if needed....best thing its supplied free too...i cant believe they supply the rescue drugs as well...they must want our business bad

by Rockerforlife, Nov 30, 2008 10:02AM
You should see my baby brother...hes the spitting image of Mel Gibson

by Rockerforlife, Nov 30, 2008 10:09AM
To: SONG FOR MARCIA
http://www.youtube.com/watch?v=j4y-RzVGrHg

by Marcia2202, Nov 30, 2008 10:11AM
To: Rock
That's great news that you get the rescues. What a great trial! I know you will beat it this time!

I'll pass on Mel Gibson.... Sorry about that

by Rockerforlife, Nov 30, 2008 10:15AM
ONE OF MY FAVOURITE SONGS....GIVES MY GOOSEBUMPS UP MY ARMS AND NECK.....this band is from vancouver canada


http://www.youtube.com/watch?v=76i6aZgo2io

by Marcia2202, Nov 30, 2008 10:22AM
Thanks for the tunes Rock...

by Rockerforlife, Nov 30, 2008 10:31AM
Hey....not a problem....thats why im here.....LOL

by Rockerforlife, Nov 30, 2008 10:39AM
To: SUNDAY SONGS
http://www.youtube.com/watch?v=VsN5MtKtWcg



a feel good song

by Rockerforlife, Nov 30, 2008 10:43AM
To: SUNDAY SONGS
http://www.youtube.com/watch?v=VsN5MtKtWcg

by Rockerforlife, Nov 30, 2008 10:49AM
To: TIME
http://www.youtube.com/watch?v=VsN5MtKtWcg

by geterdone, Nov 30, 2008 11:01AM
To: rocker
And just think it only took 20/30 years to get us here to this point. Good Luck with the Boceprerir induction and may the sides be minimual.

jasper

by Rockerforlife, Nov 30, 2008 11:07AM
To: WELCOME TO THE MACHIME
http://www.veoh.com/videos/v158315782kfjCE7k?rank=120&jsonParams=%7B%22numResults%22%3A20%2C%22rlmin%22%3A0%2C%22query%22%3A%22PINK+FLOYD%22%2C%22rlmax%22%3Anull%2C%22veohOnly%22%3Atrue%2C%22contentRatingId%22%3A2%2C%22order%22%3A%22default%22%2C%22range%22%3A%22a%22%2C%22sId%22%3A%22212026817431610417%22%2C%22offset%22%3A120%7D&searchId=212026817431610417&rank=121

by Rockerforlife, Nov 30, 2008 11:13AM
I HAVE NO SIDES on the SOC drugs....i pray for the same with the BOC drugs....i get the funny feeling im goona be hit hard

by Rockerforlife, Nov 30, 2008 11:17AM
To: SOUP
1 CUP FROZEN VEGGIES
4 CUPS WATER
1 ORGANIC BULLION CUBE
1/2 CUP PASTA



DONE DEAL

by geterdone